N-Bromosuccinimide-Fluorescein Based Sensitive Flow-Injection Chemiluminescence Determination of Phenformin

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N-bromosuccinimide-fluorescein based sensitive flow-injection chemiluminescence determination of phenformin.

A novel and highly sensitive method for the determination of phenformin over the range of 6 x 10(-9) - 1 x 10(-5) g ml(-1) in pharmaceutical formulations with flow-injection chemiluminescence (CL) detection is proposed. The method is based on the CL produced during the oxidation of N-bromosuccinimide (NBS) in an alkaline medium in the presence of fluorescein as an effective energy transfer agen...

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ژورنال

عنوان ژورنال: Analytical Sciences

سال: 2004

ISSN: 0910-6340,1348-2246

DOI: 10.2116/analsci.20.319